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The effects of phenotypic plasticity on the fixation probability of mutant cancer stem cells.
Eastman B, Wodarz D, Kohandel M. Eastman B, et al. J Theor Biol. 2020 Oct 21;503:110384. doi: 10.1016/j.jtbi.2020.110384. Epub 2020 Jun 27. J Theor Biol. 2020. PMID: 32603669 Free PMC article.
Two recent papers have considered how this rate of plasticity affects the evolutionary dynamic of an invasive, malignant population of stem cells and differentiated cells into existing tissue (Mahdipour-Shirayeh et al., 2017; Wodarz, 2018). These papers arrive at seemingly …
Two recent papers have considered how this rate of plasticity affects the evolutionary dynamic of an invasive, malignant population of stem …
Amniotic fluid-derived exosomes attenuated fibrotic changes in POI rats through modulation of the TGF-β/Smads signaling pathway.
Nazdikbin Yamchi N, Ahmadian S, Mobarak H, Amjadi F, Beheshti R, Tamadon A, Rahbarghazi R, Mahdipour M. Nazdikbin Yamchi N, et al. J Ovarian Res. 2023 Jun 27;16(1):118. doi: 10.1186/s13048-023-01214-1. J Ovarian Res. 2023. PMID: 37370156 Free PMC article.
Four weeks later, we measured the serum levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2), and performed histopathological evaluations using H & E and Masson's trichrome staining. We also monitored the expression of genes relate …
Four weeks later, we measured the serum levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2), and perf …
Synergistic effect of chitosan-alginate composite hydrogel enriched with ascorbic acid and alpha-tocopherol under hypoxic conditions on the behavior of mesenchymal stem cells for wound healing.
Ghahremani-Nasab M, Akbari-Gharalari N, Rahmani Del Bakhshayesh A, Ghotaslou A, Ebrahimi-Kalan A, Mahdipour M, Mehdipour A. Ghahremani-Nasab M, et al. Stem Cell Res Ther. 2023 Nov 13;14(1):326. doi: 10.1186/s13287-023-03567-2. Stem Cell Res Ther. 2023. PMID: 37953287 Free PMC article.
The survival rate was analyzed using MTT assay test. The hydrogels were also investigated by DAPI and H&E staining to monitor cell proliferation and viability. To induce hypoxia, the cells were exposed to CoCl(2). ...Also, based on wettability and hemolysis tests of th …
The survival rate was analyzed using MTT assay test. The hydrogels were also investigated by DAPI and H&E staining to monitor cel …
Classical music restored fertility status in rat model of premature ovarian failure.
Nazdikbin Yamchi N, Alizadeh Ashrafi MM, Abbasi H, Amjadi F, Geranmayeh MH, Shirazi R, Tamadon A, Rahbarghazi R, Mahdipour M. Nazdikbin Yamchi N, et al. BMC Complement Med Ther. 2022 Nov 9;22(1):290. doi: 10.1186/s12906-022-03759-y. BMC Complement Med Ther. 2022. PMID: 36352380 Free PMC article.
METHODS: Mozart's piano classical music (K.448) was used for up to 4 and 8 weeks. Rats were exposed to music 6 h every day using a stereo system with a volume of 65-70 dB. Sera and ovarian tissue samples were collected for the evaluation of FSH, LH, and E(2) and histopatho …
METHODS: Mozart's piano classical music (K.448) was used for up to 4 and 8 weeks. Rats were exposed to music 6 h every day using a st …
Intratesticular versus intraperitoneal injection of Busulfan for the induction of azoospermia in a rat model.
Mobarak H, Rahbarghazi R, Nouri M, Heidarpour M, Mahdipour M. Mobarak H, et al. BMC Pharmacol Toxicol. 2022 Jul 14;23(1):50. doi: 10.1186/s40360-022-00587-1. BMC Pharmacol Toxicol. 2022. PMID: 35831882 Free PMC article.
Blood, bone marrow, liver, renal, and testes samples were collected for histological (H&E staining), biochemical (serum levels of ALT, AST, ALP, creatinine, and urea), and hematological analyses. ...
Blood, bone marrow, liver, renal, and testes samples were collected for histological (H&E staining), biochemical (serum levels of …
Bacterial Lipase Neutralized Toxicity of Lipopolysaccharide on Chicken Embryo Cardiac Tissue.
Bagherzadeh A, Vaziri H, Nasimi FS, Ahmadian S, Feyzi A, Farhadi M, Yahyavi F, Hashemi B, Rahbarghazi R, Mahdipour M. Bagherzadeh A, et al. Cardiovasc Toxicol. 2021 Jul;21(7):582-591. doi: 10.1007/s12012-021-09651-4. Epub 2021 Apr 15. Cardiovasc Toxicol. 2021. PMID: 33856644
Microvascular density and anterior wall thickness were monitored in histological samples using H&E staining. High dose of LPS (1 mg/kbw) increased the expression of TRIF but not NF-kB compared to the control group (p < 0.05). ...
Microvascular density and anterior wall thickness were monitored in histological samples using H&E staining. High dose of LPS (1 …
Light-emitting diode photomodulation of uterine adenocarcinoma cells inhibited angiogenesis capacity via the regulation of exosome biogenesis.
Mojtahedin S, Nasimi FS, Tajalli H, Ebrahimi S, Alimohammadzadeh B, Rahbarghazi R, Mahdipour M. Mojtahedin S, et al. Lasers Med Sci. 2022 Oct;37(8):3193-3201. doi: 10.1007/s10103-022-03597-x. Epub 2022 Jun 21. Lasers Med Sci. 2022. PMID: 35727394
To this end, cells were exposed to different energy densities (fluences) of 4, 8, 16, 32, and 64 J/cm(2) for 5 days (once every 24 h), and cell viability was determined using an MTT assay. Based on data from the MTT panel, cells were exposed to 4 and 16 J/cm(2) for subsequ …
To this end, cells were exposed to different energy densities (fluences) of 4, 8, 16, 32, and 64 J/cm(2) for 5 days (once every 24 h) …
Melatonin blunted the angiogenic activity in 3D colon cancer tumoroids by the reduction of endocan.
Narmi MT, Shoja HM, Haiaty S, Mahdipour M, Rahbarghazi R. Narmi MT, et al. Cancer Cell Int. 2023 Jun 19;23(1):118. doi: 10.1186/s12935-023-02951-5. Cancer Cell Int. 2023. PMID: 37337165 Free PMC article.
Tumoroids were exposed to different concentrations of melatonin, from 0.005 to 0.8 mM and 4 to 10 mM, for 48 h. The survival rate was measured by MTT and LDH leakage assays. Protein levels of endocan and VEGF were assessed using western blotting. Using histological examina …
Tumoroids were exposed to different concentrations of melatonin, from 0.005 to 0.8 mM and 4 to 10 mM, for 48 h. The survival rate was …
Toxic effects of VCD on kidneys and liver tissues: a histopathological and biochemical study.
Ahmadian S, Sheshpari S, Mahdipour M, Pazhang M, Tsai PJ, Nouri M, Rahbarghazi R, Shahnazi M. Ahmadian S, et al. BMC Res Notes. 2019 Jul 22;12(1):446. doi: 10.1186/s13104-019-4490-y. BMC Res Notes. 2019. PMID: 31331386 Free PMC article.
At the respective time point, rats were euthanized, blood and tissue samples were collected. H&E staining was performed to evaluate pathological changes. Serum level of ALT, AST, creatinine and urea were also measured. ...
At the respective time point, rats were euthanized, blood and tissue samples were collected. H&E staining was performed to evalua …
Ultrasound-assisted synthesis of MIL-88(Fe) coordinated to carboxymethyl cellulose fibers: A safe carrier for highly sustained release of tetracycline.
Darvishi S, Javanbakht S, Heydari A, Kazeminava F, Gholizadeh P, Mahdipour M, Shaabani A. Darvishi S, et al. Int J Biol Macromol. 2021 Jun 30;181:937-944. doi: 10.1016/j.ijbiomac.2021.04.092. Epub 2021 Apr 18. Int J Biol Macromol. 2021. PMID: 33878359
The release profile in the simulated physiological conditions, pH 7.4, revealed a low initial burst release followed by a sustained and prolonged release over 384 h. The in vitro cytotoxicity of CMC/MIL-88(Fe) against Human skin fibroblast (HFF-1) cells was calculated by M …
The release profile in the simulated physiological conditions, pH 7.4, revealed a low initial burst release followed by a sustained and prol …
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